2016 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida State | 1 | 290 | 160 | 55 | 450 | 8.18 | 450.0 |
| 2 | Pittsburgh | 1 | 104 | 240 | 62 | 344 | 5.55 | 344.0 |
| 3 | Clemson | 1 | 141 | 245 | 78 | 386 | 4.95 | 386.0 |
| 4 | Georgia Tech | 1 | 167 | 168 | 83 | 335 | 4.04 | 335.0 |
| 5 | Duke | 2 | 318 | 430 | 128 | 748 | 5.84 | 374.0 |
| 6 | Virginia Tech | 2 | 281 | 611 | 139 | 892 | 6.42 | 446.0 |
| 7 | Virginia | 2 | 216 | 556 | 143 | 772 | 5.40 | 386.0 |
| 8 | Boston College | 3 | -3 | 313 | 150 | 310 | 2.07 | 103.3 |
| 9 | North Carolina State | 3 | 324 | 555 | 199 | 879 | 4.42 | 293.0 |
| 10 | Louisville | 3 | 260 | 517 | 206 | 777 | 3.77 | 259.0 |
| 11 | Miami (Florida) | 3 | 339 | 545 | 209 | 884 | 4.23 | 294.7 |
| 12 | Wake Forest | 3 | 364 | 675 | 215 | 1039 | 4.83 | 346.3 |
| 13 | Syracuse | 3 | 561 | 972 | 227 | 1533 | 6.75 | 511.0 |