2016 Louisville Cardinals Total Defense Split Stats through 01/09/2017
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 13 | 1497 | 2692 | 894 | 4189 | 4.69 | 322.2 |
| at Home | 6 | 645 | 1131 | 396 | 1776 | 4.48 | 296.0 |
| on Road/Neutral Site | 7 | 852 | 1561 | 498 | 2413 | 4.85 | 344.7 |
| in Wins | 9 | 826 | 1519 | 611 | 2345 | 3.84 | 260.6 |
| in Losses | 4 | 671 | 1173 | 283 | 1844 | 6.52 | 461.0 |
| vs. Conference | 8 | 831 | 1606 | 546 | 2437 | 4.46 | 304.6 |
| vs. Non-Conference | 5 | 666 | 1086 | 348 | 1752 | 5.03 | 350.4 |
| vs. Ranked (AP) | 3 | 549 | 636 | 199 | 1185 | 5.95 | 395.0 |
| vs. Unranked (AP) | 10 | 948 | 2056 | 695 | 3004 | 4.32 | 300.4 |
| vs. FBS (I-A) | 13 | 1497 | 2692 | 894 | 4189 | 4.69 | 322.2 |
| vs. FCS (I-AA) | 0 | 0 | 0 | 0 | 0 | - | - |
| vs. FBS Winning | 8 | 986 | 1813 | 546 | 2799 | 5.13 | 349.9 |
| vs. FBS Non-Winning | 5 | 511 | 879 | 348 | 1390 | 3.99 | 278.0 |
| vs. FBS Power 5 | 10 | 1237 | 2175 | 688 | 3412 | 4.96 | 341.2 |
| vs. FBS non-Power 5 | 3 | 260 | 517 | 206 | 777 | 3.77 | 259.0 |
| in August/September | 4 | 488 | 625 | 287 | 1113 | 3.88 | 278.3 |
| in October | 4 | 409 | 909 | 251 | 1318 | 5.25 | 329.5 |
| in November | 4 | 423 | 941 | 286 | 1364 | 4.77 | 341.0 |
| in December/January | 1 | 177 | 217 | 70 | 394 | 5.63 | 394.0 |