2018 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Louisville | 1 | 168 | 260 | 81 | 428 | 5.28 | 428.0 |
| 2 | North Carolina | 1 | 220 | 290 | 82 | 510 | 6.22 | 510.0 |
| 3 | Miami (Florida) | 2 | 129 | 392 | 111 | 521 | 4.69 | 260.5 |
| 4 | Clemson | 2 | 168 | 220 | 121 | 388 | 3.21 | 194.0 |
| 5 | Virginia | 2 | 323 | 395 | 132 | 718 | 5.44 | 359.0 |
| 6 | Florida State | 2 | 371 | 345 | 136 | 716 | 5.26 | 358.0 |
| 7 | Duke | 2 | 221 | 425 | 143 | 646 | 4.52 | 323.0 |
| 8 | Boston College | 2 | 257 | 511 | 149 | 768 | 5.15 | 384.0 |
| 8 | Pittsburgh | 2 | 320 | 592 | 149 | 912 | 6.12 | 456.0 |
| 10 | Georgia Tech | 2 | 282 | 537 | 161 | 819 | 5.09 | 409.5 |
| 11 | North Carolina State | 3 | 192 | 585 | 181 | 777 | 4.29 | 259.0 |
| 12 | Syracuse | 3 | 591 | 888 | 206 | 1479 | 7.18 | 493.0 |
| 13 | Virginia Tech | 4 | 792 | 1192 | 288 | 1984 | 6.89 | 496.0 |
| 14 | Wake Forest | 4 | 870 | 880 | 313 | 1750 | 5.59 | 437.5 |