2016 Conference USA Leaders Total Defense - Games Lost Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Old Dominion | 3 | 634 | 875 | 209 | 1509 | 7.22 | 503.0 |
| 2 | Western Kentucky | 3 | 341 | 1084 | 224 | 1425 | 6.36 | 475.0 |
| 3 | Southern Mississippi | 6 | 1292 | 1145 | 345 | 2437 | 7.06 | 406.2 |
| 4 | Louisiana Tech | 5 | 818 | 1780 | 376 | 2598 | 6.91 | 519.6 |
| 5 | Middle Tennessee | 5 | 1043 | 1153 | 381 | 2196 | 5.76 | 439.2 |
| 6 | UTSA | 7 | 1404 | 1482 | 476 | 2886 | 6.06 | 412.3 |
| 7 | UTEP | 8 | 1863 | 1768 | 534 | 3631 | 6.80 | 453.9 |
| 8 | Florida International | 8 | 1690 | 2075 | 556 | 3765 | 6.77 | 470.6 |
| 9 | North Texas | 8 | 2189 | 1759 | 562 | 3948 | 7.02 | 493.5 |
| 10 | Charlotte | 8 | 1268 | 2518 | 582 | 3786 | 6.51 | 473.3 |
| 11 | Rice | 9 | 2202 | 2900 | 639 | 5102 | 7.98 | 566.9 |
| 12 | Marshall | 9 | 2030 | 2474 | 664 | 4504 | 6.78 | 500.4 |
| 13 | Florida Atlantic | 9 | 2406 | 2435 | 669 | 4841 | 7.24 | 537.9 |