2016 Conference USA Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Rice | 9 | 1754 | 2671 | 597 | 4425 | 7.41 | 491.7 |
| 2 | Southern Mississippi | 10 | 1659 | 1655 | 605 | 3314 | 5.48 | 331.4 |
| 3 | Marshall | 9 | 1849 | 2172 | 641 | 4021 | 6.27 | 446.8 |
| 4 | Florida Atlantic | 9 | 2187 | 2484 | 664 | 4671 | 7.03 | 519.0 |
| 5 | Florida International | 10 | 1900 | 2352 | 677 | 4252 | 6.28 | 425.2 |
| 6 | UTSA | 10 | 1579 | 2330 | 686 | 3909 | 5.70 | 390.9 |
| 7 | UTEP | 10 | 2216 | 2173 | 688 | 4389 | 6.38 | 438.9 |
| 8 | Charlotte | 10 | 1352 | 3005 | 747 | 4357 | 5.83 | 435.7 |
| 9 | Old Dominion | 11 | 1795 | 2414 | 765 | 4209 | 5.50 | 382.6 |
| 10 | Western Kentucky | 11 | 1041 | 3143 | 783 | 4184 | 5.34 | 380.4 |
| 11 | Louisiana Tech | 11 | 1589 | 3048 | 800 | 4637 | 5.80 | 421.5 |
| 12 | North Texas | 11 | 2702 | 2313 | 819 | 5015 | 6.12 | 455.9 |
| 13 | Middle Tennessee | 10 | 1912 | 2812 | 840 | 4724 | 5.62 | 472.4 |