2016 Conference USA Leaders Total Defense - Games vs. Conference Teams Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 8 | 1316 | 1437 | 459 | 2753 | 6.00 | 344.1 |
| 2 | Rice | 8 | 1406 | 2605 | 522 | 4011 | 7.68 | 501.4 |
| 3 | Florida International | 8 | 1508 | 1849 | 523 | 3357 | 6.42 | 419.6 |
| 4 | UTEP | 8 | 1651 | 1793 | 536 | 3444 | 6.43 | 430.5 |
| 5 | Old Dominion | 8 | 1226 | 1692 | 543 | 2918 | 5.37 | 364.8 |
| 6 | UTSA | 8 | 1140 | 2145 | 558 | 3285 | 5.89 | 410.6 |
| 7 | Marshall | 8 | 1704 | 1793 | 579 | 3497 | 6.04 | 437.1 |
| 8 | North Texas | 8 | 1648 | 1866 | 580 | 3514 | 6.06 | 439.3 |
| 9 | Florida Atlantic | 8 | 1961 | 2222 | 584 | 4183 | 7.16 | 522.9 |
| 10 | Charlotte | 8 | 1070 | 2423 | 620 | 3493 | 5.63 | 436.6 |
| 11 | Western Kentucky | 9 | 883 | 2386 | 623 | 3269 | 5.25 | 363.2 |
| 12 | Louisiana Tech | 9 | 1158 | 2621 | 666 | 3779 | 5.67 | 419.9 |
| 13 | Middle Tennessee | 8 | 1403 | 2388 | 674 | 3791 | 5.62 | 473.9 |