2025 American Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 09/12/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Rice | 1 | 151 | 88 | 59 | 239 | 4.05 | 239.0 |
| 2 | Tulsa | 1 | 39 | 252 | 71 | 291 | 4.10 | 291.0 |
| 3 | Temple | 1 | 103 | 199 | 62 | 302 | 4.87 | 302.0 |
| 4 | North Texas | 1 | 216 | 87 | 71 | 303 | 4.27 | 303.0 |
| 5 | USF | 1 | 122 | 256 | 86 | 378 | 4.40 | 378.0 |
| 6 | Memphis | 1 | 49 | 340 | 68 | 389 | 5.72 | 389.0 |
| 7 | Navy | 1 | 92 | 321 | 60 | 413 | 6.88 | 413.0 |
| 8 | Tulane | 1 | 190 | 231 | 65 | 421 | 6.48 | 421.0 |
| 9 | UTSA | 1 | 168 | 286 | 66 | 454 | 6.88 | 454.0 |
| 10 | UAB | 1 | 295 | 168 | 59 | 463 | 7.85 | 463.0 |
| 11 | Charlotte | 1 | 182 | 404 | 88 | 586 | 6.66 | 586.0 |