2025 American Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 09/13/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | East Carolina | 1 | 67 | 172 | 65 | 239 | 3.68 | 239.0 |
| 2 | Rice | 1 | 151 | 88 | 59 | 239 | 4.05 | 239.0 |
| 3 | Memphis | 2 | 89 | 412 | 123 | 501 | 4.07 | 250.5 |
| 4 | North Texas | 1 | 216 | 87 | 71 | 303 | 4.27 | 303.0 |
| 5 | USF | 1 | 122 | 256 | 86 | 378 | 4.40 | 378.0 |
| 6 | Temple | 1 | 103 | 199 | 62 | 302 | 4.87 | 302.0 |
| 7 | Tulsa | 2 | 406 | 346 | 144 | 752 | 5.22 | 376.0 |
| 8 | Navy | 2 | 232 | 510 | 130 | 742 | 5.71 | 371.0 |
| 9 | Florida Atlantic | 1 | 224 | 184 | 64 | 408 | 6.38 | 408.0 |
| 10 | Tulane | 1 | 190 | 231 | 65 | 421 | 6.48 | 421.0 |
| 11 | UAB | 2 | 454 | 450 | 137 | 904 | 6.60 | 452.0 |
| 12 | Charlotte | 1 | 182 | 404 | 88 | 586 | 6.66 | 586.0 |
| 13 | UTSA | 1 | 168 | 286 | 66 | 454 | 6.88 | 454.0 |