2025 Atlantic Coast Conference Leaders Total Defense - Games in October Only through 11/15/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Duke | 2 | 212 | 450 | 118 | 662 | 5.61 | 331.0 |
| 2 | Wake Forest | 3 | 361 | 457 | 210 | 818 | 3.90 | 272.7 |
| 3 | Miami (FL) | 3 | 306 | 609 | 204 | 915 | 4.49 | 305.0 |
| 3 | Clemson | 3 | 281 | 634 | 192 | 915 | 4.77 | 305.0 |
| 5 | Louisville | 3 | 267 | 664 | 204 | 931 | 4.56 | 310.3 |
| 6 | Virginia | 3 | 334 | 720 | 212 | 1054 | 4.97 | 351.3 |
| 7 | Florida State | 3 | 384 | 723 | 197 | 1107 | 5.62 | 369.0 |
| 8 | Virginia Tech | 3 | 398 | 755 | 205 | 1153 | 5.62 | 384.3 |
| 9 | Georgia Tech | 3 | 411 | 778 | 194 | 1189 | 6.13 | 396.3 |
| 10 | North Carolina | 4 | 341 | 852 | 260 | 1193 | 4.59 | 298.3 |
| 11 | NC State | 3 | 316 | 886 | 218 | 1202 | 5.51 | 400.7 |
| 12 | California | 3 | 655 | 551 | 207 | 1206 | 5.83 | 402.0 |
| 13 | Stanford | 3 | 454 | 763 | 206 | 1217 | 5.91 | 405.7 |
| 14 | Pittsburgh | 4 | 434 | 854 | 241 | 1288 | 5.34 | 322.0 |
| 15 | SMU | 4 | 305 | 1090 | 296 | 1395 | 4.71 | 348.8 |
| 16 | Syracuse | 4 | 640 | 954 | 261 | 1594 | 6.11 | 398.5 |
| 17 | Boston College | 4 | 808 | 1158 | 281 | 1966 | 7.00 | 491.5 |