2025 Atlantic Coast Conference Leaders Total Defense - Games at Home Only through 09/11/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Boston College | 1 | 16 | 152 | 66 | 168 | 2.55 | 168.0 |
| 2 | California | 1 | 52 | 140 | 58 | 192 | 3.31 | 192.0 |
| 3 | Virginia | 1 | 91 | 163 | 67 | 254 | 3.79 | 254.0 |
| 4 | Georgia Tech | 1 | 117 | 209 | 77 | 326 | 4.23 | 326.0 |
| 5 | Louisville | 2 | 200 | 213 | 131 | 413 | 3.15 | 206.5 |
| 6 | Syracuse | 1 | 142 | 274 | 78 | 416 | 5.33 | 416.0 |
| 7 | Pittsburgh | 2 | 69 | 348 | 126 | 417 | 3.31 | 208.5 |
| 8 | Virginia Tech | 1 | 262 | 228 | 57 | 490 | 8.60 | 490.0 |
| 9 | Miami (FL) | 2 | 185 | 320 | 109 | 505 | 4.63 | 252.5 |
| 10 | Florida State | 2 | 192 | 346 | 121 | 538 | 4.45 | 269.0 |
| 11 | North Carolina | 1 | 258 | 284 | 72 | 542 | 7.53 | 542.0 |
| 12 | Clemson | 2 | 186 | 471 | 133 | 657 | 4.94 | 328.5 |
| 13 | Duke | 2 | 286 | 408 | 135 | 694 | 5.14 | 347.0 |
| 14 | NC State | 2 | 287 | 640 | 149 | 927 | 6.22 | 463.5 |
| 15 | Wake Forest | 3 | 397 | 554 | 228 | 951 | 4.17 | 317.0 |
| 16 | SMU | 2 | 268 | 684 | 172 | 952 | 5.53 | 476.0 |