2025 Atlantic Coast Conference Leaders Total Defense - Games in November Only through 11/15/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Syracuse | 1 | 124 | 261 | 57 | 385 | 6.75 | 385.0 |
| 2 | Pittsburgh | 2 | 165 | 548 | 139 | 713 | 5.13 | 356.5 |
| 3 | Stanford | 2 | 212 | 507 | 125 | 719 | 5.75 | 359.5 |
| 4 | Virginia | 3 | 189 | 532 | 179 | 721 | 4.03 | 240.3 |
| 5 | North Carolina | 2 | 259 | 475 | 138 | 734 | 5.32 | 367.0 |
| 6 | Virginia Tech | 2 | 472 | 330 | 133 | 802 | 6.03 | 401.0 |
| 7 | California | 2 | 342 | 465 | 149 | 807 | 5.42 | 403.5 |
| 8 | SMU | 2 | 257 | 558 | 163 | 815 | 5.00 | 407.5 |
| 9 | Miami (FL) | 3 | 207 | 609 | 191 | 816 | 4.27 | 272.0 |
| 10 | Florida State | 3 | 421 | 508 | 193 | 929 | 4.81 | 309.7 |
| 11 | Louisville | 3 | 362 | 613 | 202 | 975 | 4.83 | 325.0 |
| 12 | Wake Forest | 3 | 369 | 636 | 182 | 1005 | 5.52 | 335.0 |
| 13 | Georgia Tech | 2 | 418 | 702 | 133 | 1120 | 8.42 | 560.0 |
| 14 | NC State | 2 | 365 | 775 | 140 | 1140 | 8.14 | 570.0 |
| 15 | Clemson | 3 | 359 | 825 | 192 | 1184 | 6.17 | 394.7 |
| 16 | Duke | 3 | 555 | 1012 | 219 | 1567 | 7.16 | 522.3 |
| 17 | Boston College | 3 | 638 | 1022 | 197 | 1660 | 8.43 | 553.3 |