2025 Atlantic Coast Conference Leaders Total Defense - Games in November Only through 12/06/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Virginia | 4 | 308 | 610 | 226 | 918 | 4.06 | 229.5 |
| 2 | Syracuse | 3 | 589 | 624 | 151 | 1213 | 8.03 | 404.3 |
| 3 | Miami (FL) | 5 | 431 | 1009 | 306 | 1440 | 4.71 | 288.0 |
| 4 | North Carolina | 4 | 621 | 851 | 286 | 1472 | 5.15 | 368.0 |
| 5 | SMU | 4 | 507 | 988 | 289 | 1495 | 5.17 | 373.8 |
| 6 | Pittsburgh | 4 | 426 | 1081 | 284 | 1507 | 5.31 | 376.8 |
| 7 | Stanford | 4 | 411 | 1129 | 275 | 1540 | 5.60 | 385.0 |
| 8 | California | 4 | 728 | 838 | 273 | 1566 | 5.74 | 391.5 |
| 9 | Louisville | 5 | 580 | 1020 | 328 | 1600 | 4.88 | 320.0 |
| 9 | Virginia Tech | 4 | 752 | 848 | 279 | 1600 | 5.73 | 400.0 |
| 11 | Florida State | 5 | 827 | 828 | 330 | 1655 | 5.02 | 331.0 |
| 12 | Wake Forest | 5 | 546 | 1137 | 332 | 1683 | 5.07 | 336.6 |
| 13 | NC State | 4 | 615 | 1173 | 266 | 1788 | 6.72 | 447.0 |
| 14 | Georgia Tech | 4 | 794 | 998 | 267 | 1792 | 6.71 | 448.0 |
| 15 | Clemson | 5 | 466 | 1411 | 323 | 1877 | 5.81 | 375.4 |
| 16 | Boston College | 4 | 827 | 1087 | 256 | 1914 | 7.48 | 478.5 |
| 17 | Duke | 5 | 782 | 1563 | 347 | 2345 | 6.76 | 469.0 |