2025 Big 12 Conference Leaders Passes Defended - Games in October Only through 10/16/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 2 | 2 | 12 | 14 | 7.00 |
| 1 | Cincinnati | 2 | 0 | 14 | 14 | 7.00 |
| 3 | Texas Tech | 2 | 2 | 11 | 13 | 6.50 |
| 4 | Arizona | 2 | 3 | 9 | 12 | 6.00 |
| 4 | Kansas | 2 | 1 | 11 | 12 | 6.00 |
| 6 | BYU | 2 | 3 | 8 | 11 | 5.50 |
| 7 | Kansas State | 2 | 3 | 7 | 10 | 5.00 |
| 8 | TCU | 2 | 3 | 6 | 9 | 4.50 |
| 8 | Houston | 2 | 1 | 8 | 9 | 4.50 |
| 10 | Baylor | 1 | 1 | 4 | 5 | 5.00 |
| 10 | Utah | 1 | 0 | 5 | 5 | 5.00 |
| 12 | Iowa State | 2 | 0 | 4 | 4 | 2.00 |
| 13 | Colorado | 2 | 1 | 2 | 3 | 1.50 |
| 13 | UCF | 2 | 0 | 3 | 3 | 1.50 |
| 15 | West Virginia | 1 | 1 | 1 | 2 | 2.00 |
| 16 | Arizona State | 1 | 0 | 1 | 1 | 1.00 |