2025 Big 12 Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 09/18/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 1 | 22 | 8 | 0.36 | 0 | 22.00 | 8.00 |
| 1 | BYU | 1 | 24 | 19 | 0.79 | 0 | 24.00 | 19.00 |
| 1 | Arizona State | 1 | 30 | 66 | 2.20 | 0 | 30.00 | 66.00 |
| 1 | Utah | 1 | 28 | 84 | 3.00 | 0 | 28.00 | 84.00 |
| 1 | Cincinnati | 1 | 36 | 110 | 3.06 | 0 | 36.00 | 110.00 |
| 6 | West Virginia | 1 | 34 | 46 | 1.35 | 1 | 34.00 | 46.00 |
| 6 | TCU | 1 | 28 | 50 | 1.79 | 1 | 28.00 | 50.00 |
| 8 | Houston | 1 | 23 | 96 | 4.17 | 2 | 23.00 | 96.00 |
| 8 | Arizona | 1 | 24 | 105 | 4.38 | 2 | 24.00 | 105.00 |
| 8 | Iowa State | 2 | 66 | 241 | 3.65 | 2 | 33.00 | 120.50 |
| 8 | Kansas | 1 | 47 | 261 | 5.55 | 2 | 47.00 | 261.00 |
| 12 | Kansas State | 2 | 91 | 364 | 4.00 | 3 | 45.50 | 182.00 |
| 13 | Oklahoma State | 1 | 37 | 312 | 8.43 | 5 | 37.00 | 312.00 |
| 14 | Colorado | 2 | 100 | 529 | 5.29 | 6 | 50.00 | 264.50 |
| 15 | Baylor | 2 | 96 | 470 | 4.90 | 7 | 48.00 | 235.00 |