2025 Big 12 Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 12/13/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 11 | 327 | 774 | 2.37 | 5 | 29.73 | 70.36 |
| 2 | Iowa State | 10 | 311 | 1413 | 4.54 | 13 | 31.10 | 141.30 |
| 3 | BYU | 11 | 373 | 1473 | 3.95 | 11 | 33.91 | 133.91 |
| 4 | Arizona State | 10 | 340 | 1192 | 3.51 | 16 | 34.00 | 119.20 |
| 5 | Houston | 10 | 350 | 1384 | 3.95 | 15 | 35.00 | 138.40 |
| 6 | TCU | 11 | 387 | 1435 | 3.71 | 8 | 35.18 | 130.45 |
| 7 | UCF | 10 | 370 | 1483 | 4.01 | 16 | 37.00 | 148.30 |
| 8 | Oklahoma State | 10 | 377 | 1670 | 4.43 | 18 | 37.70 | 167.00 |
| 9 | Arizona | 10 | 381 | 1565 | 4.11 | 16 | 38.10 | 156.50 |
| 9 | Kansas State | 10 | 381 | 1626 | 4.27 | 17 | 38.10 | 162.60 |
| 9 | Kansas | 10 | 381 | 1987 | 5.22 | 18 | 38.10 | 198.70 |
| 12 | Utah | 10 | 389 | 2008 | 5.16 | 15 | 38.90 | 200.80 |
| 13 | West Virginia | 10 | 394 | 1490 | 3.78 | 14 | 39.40 | 149.00 |
| 14 | Baylor | 11 | 449 | 2271 | 5.06 | 30 | 40.82 | 206.45 |
| 15 | Cincinnati | 10 | 417 | 1917 | 4.60 | 16 | 41.70 | 191.70 |
| 16 | Colorado | 10 | 438 | 2421 | 5.53 | 25 | 43.80 | 242.10 |