2025 Big 12 Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 11/04/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 7 | 219 | 555 | 2.53 | 4 | 31.29 | 79.29 |
| 2 | TCU | 7 | 248 | 778 | 3.14 | 4 | 35.43 | 111.14 |
| 3 | Houston | 7 | 258 | 993 | 3.85 | 12 | 36.86 | 141.86 |
| 3 | Arizona | 6 | 240 | 924 | 3.85 | 11 | 40.00 | 154.00 |
| 5 | UCF | 6 | 216 | 846 | 3.92 | 7 | 36.00 | 141.00 |
| 6 | Arizona State | 7 | 227 | 901 | 3.97 | 13 | 32.43 | 128.71 |
| 7 | Kansas State | 7 | 255 | 1036 | 4.06 | 10 | 36.43 | 148.00 |
| 8 | Utah | 7 | 263 | 1113 | 4.23 | 8 | 37.57 | 159.00 |
| 9 | West Virginia | 7 | 263 | 1128 | 4.29 | 12 | 37.57 | 161.14 |
| 10 | BYU | 6 | 213 | 921 | 4.32 | 8 | 35.50 | 153.50 |
| 11 | Cincinnati | 7 | 274 | 1233 | 4.50 | 9 | 39.14 | 176.14 |
| 12 | Oklahoma State | 7 | 263 | 1205 | 4.58 | 16 | 37.57 | 172.14 |
| 13 | Baylor | 8 | 323 | 1503 | 4.65 | 18 | 40.38 | 187.88 |
| 14 | Iowa State | 7 | 237 | 1141 | 4.81 | 10 | 33.86 | 163.00 |
| 15 | Kansas | 7 | 271 | 1440 | 5.31 | 15 | 38.71 | 205.71 |
| 16 | Colorado | 7 | 297 | 1693 | 5.70 | 17 | 42.43 | 241.86 |