2025 Conference USA Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Delaware | 6 | 50 | 77 | 20 | 147 | 24.5 |
| 2 | Sam Houston State | 7 | 47 | 63 | 16 | 126 | 18.0 |
| 3 | New Mexico State | 7 | 36 | 75 | 14 | 125 | 17.9 |
| 4 | Louisiana Tech | 6 | 65 | 56 | 12 | 133 | 22.2 |
| 4 | Middle Tennessee State | 6 | 36 | 77 | 12 | 125 | 20.8 |
| 4 | UTEP | 6 | 37 | 51 | 12 | 100 | 16.7 |
| 7 | Jacksonville State | 6 | 79 | 38 | 11 | 128 | 21.3 |
| 8 | Western Kentucky | 8 | 53 | 107 | 10 | 170 | 21.3 |
| 9 | FIU | 6 | 41 | 66 | 9 | 116 | 19.3 |
| 10 | Missouri State | 5 | 36 | 54 | 8 | 98 | 19.6 |
| 10 | Liberty | 7 | 61 | 61 | 8 | 130 | 18.6 |
| 12 | Kennesaw State | 5 | 49 | 51 | 7 | 107 | 21.4 |