2025 Conference USA Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 11/22/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Delaware | 8 | 65 | 102 | 27 | 194 | 24.3 |
| 2 | Kennesaw State | 8 | 83 | 91 | 12 | 186 | 23.3 |
| 3 | Louisiana Tech | 8 | 90 | 72 | 18 | 180 | 22.5 |
| 4 | Western Kentucky | 9 | 64 | 124 | 11 | 199 | 22.1 |
| 5 | Jacksonville State | 9 | 115 | 60 | 17 | 192 | 21.3 |
| 5 | Missouri State | 8 | 53 | 99 | 18 | 170 | 21.3 |
| 7 | Middle Tennessee State | 9 | 54 | 114 | 19 | 187 | 20.8 |
| 8 | FIU | 9 | 69 | 94 | 17 | 180 | 20.0 |
| 9 | Liberty | 10 | 99 | 86 | 14 | 199 | 19.9 |
| 10 | New Mexico State | 9 | 52 | 104 | 22 | 178 | 19.8 |
| 11 | Sam Houston State | 9 | 56 | 88 | 22 | 166 | 18.4 |
| 12 | UTEP | 9 | 65 | 72 | 20 | 157 | 17.4 |