2025 Conference USA Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 12/13/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Jacksonville State | 11 | 138 | 75 | 22 | 235 | 21.4 |
| 2 | Kennesaw State | 10 | 102 | 112 | 20 | 234 | 23.4 |
| 3 | Liberty | 11 | 111 | 96 | 16 | 223 | 20.3 |
| 4 | Western Kentucky | 10 | 75 | 132 | 13 | 220 | 22.0 |
| 5 | Delaware | 9 | 71 | 117 | 28 | 216 | 24.0 |
| 6 | Middle Tennessee State | 10 | 58 | 129 | 20 | 207 | 20.7 |
| 7 | FIU | 10 | 79 | 105 | 20 | 204 | 20.4 |
| 8 | New Mexico State | 10 | 55 | 119 | 28 | 202 | 20.2 |
| 9 | Louisiana Tech | 9 | 104 | 76 | 20 | 200 | 22.2 |
| 10 | Missouri State | 9 | 62 | 107 | 22 | 191 | 21.2 |
| 11 | Sam Houston State | 10 | 66 | 97 | 22 | 185 | 18.5 |
| 12 | UTEP | 10 | 68 | 82 | 25 | 175 | 17.5 |