2025 Conference USA Leaders First Downs - Games vs. Ranked Teams Only (AP Poll) through 11/22/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Missouri State | 2 | 9 | 16 | 5 | 30 | 15.0 |
| 2 | New Mexico State | 1 | 7 | 14 | 3 | 24 | 24.0 |
| 2 | UTEP | 1 | 3 | 7 | 3 | 13 | 13.0 |
| 4 | Liberty | 1 | 10 | 4 | 2 | 16 | 16.0 |
| 5 | Kennesaw State | 1 | 4 | 5 | 1 | 10 | 10.0 |
| 5 | Sam Houston State | 1 | 2 | 4 | 1 | 7 | 7.0 |