2025 Conference USA Leaders Scoring Defense - Games vs. FBS Power 5 Conference Teams Only through 09/06/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jacksonville State | 1 | 2 | 1 | 2 | 0 | 0 | 17 | 17.0 |
| 1 | Louisiana Tech | 1 | 2 | 3 | 2 | 0 | 0 | 23 | 23.0 |
| 1 | Delaware | 1 | 4 | 1 | 4 | 0 | 0 | 31 | 31.0 |
| 1 | Kennesaw State | 2 | 9 | 1 | 9 | 0 | 0 | 66 | 33.0 |
| 1 | FIU | 1 | 4 | 2 | 4 | 0 | 0 | 34 | 34.0 |
| 1 | Middle Tennessee State | 1 | 6 | 0 | 6 | 0 | 0 | 42 | 42.0 |
| 1 | Missouri State | 1 | 10 | 1 | 10 | 0 | 0 | 73 | 73.0 |