2025 Conference USA Leaders Scoring Defense - Games in August/September Only through 11/01/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 5 | 7 | 6 | 6 | 1 | 0 | 68 | 13.6 |
| 1 | Western Kentucky | 5 | 12 | 10 | 11 | 0 | 0 | 113 | 22.6 |
| 1 | Liberty | 5 | 14 | 6 | 14 | 0 | 0 | 116 | 23.2 |
| 1 | Kennesaw State | 5 | 16 | 2 | 14 | 0 | 0 | 116 | 23.2 |
| 1 | New Mexico State | 4 | 13 | 4 | 12 | 1 | 0 | 104 | 26.0 |
| 1 | Delaware | 4 | 13 | 5 | 12 | 0 | 0 | 105 | 26.3 |
| 1 | UTEP | 5 | 16 | 7 | 14 | 1 | 0 | 133 | 26.6 |
| 1 | Jacksonville State | 5 | 17 | 5 | 17 | 0 | 0 | 134 | 26.8 |
| 1 | FIU | 4 | 13 | 6 | 13 | 0 | 0 | 109 | 27.3 |
| 1 | Middle Tennessee State | 5 | 20 | 5 | 20 | 0 | 0 | 155 | 31.0 |
| 1 | Missouri State | 5 | 20 | 6 | 20 | 0 | 0 | 158 | 31.6 |
| 1 | Sam Houston State | 4 | 21 | 8 | 21 | 0 | 0 | 171 | 42.8 |