2025 Conference USA Leaders Scoring Defense - Games vs. Non-Conference Teams Only through 11/22/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 8 | 5 | 8 | 0 | 0 | 71 | 17.8 |
| 1 | Western Kentucky | 4 | 8 | 8 | 8 | 0 | 0 | 80 | 20.0 |
| 1 | Liberty | 4 | 10 | 4 | 10 | 0 | 0 | 82 | 20.5 |
| 1 | New Mexico State | 4 | 13 | 2 | 13 | 0 | 0 | 97 | 24.3 |
| 1 | Kennesaw State | 4 | 14 | 1 | 13 | 0 | 0 | 100 | 25.0 |
| 1 | UTEP | 4 | 12 | 6 | 11 | 1 | 0 | 103 | 25.8 |
| 1 | Jacksonville State | 4 | 14 | 4 | 14 | 0 | 0 | 110 | 27.5 |
| 1 | FIU | 4 | 14 | 8 | 14 | 0 | 0 | 122 | 30.5 |
| 1 | Middle Tennessee State | 4 | 17 | 4 | 17 | 0 | 0 | 131 | 32.8 |
| 1 | Missouri State | 4 | 17 | 4 | 17 | 0 | 0 | 131 | 32.8 |
| 1 | Delaware | 4 | 17 | 7 | 16 | 1 | 0 | 141 | 35.3 |
| 1 | Sam Houston State | 4 | 18 | 7 | 18 | 0 | 0 | 147 | 36.8 |