2025 Conference USA Leaders Scoring Defense - Games vs. Non-Conference Teams Only through 10/08/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 3 | 4 | 5 | 4 | 0 | 0 | 43 | 14.3 |
| 2 | New Mexico State | 3 | 7 | 2 | 7 | 0 | 0 | 55 | 18.3 |
| 2 | Western Kentucky | 3 | 7 | 6 | 7 | 0 | 0 | 67 | 22.3 |
| 4 | Liberty | 4 | 10 | 4 | 10 | 0 | 0 | 82 | 20.5 |
| 5 | Delaware | 3 | 11 | 4 | 11 | 0 | 0 | 89 | 29.7 |
| 6 | UTEP | 4 | 12 | 6 | 11 | 1 | 0 | 103 | 25.8 |
| 7 | Kennesaw State | 4 | 14 | 1 | 13 | 0 | 0 | 100 | 25.0 |
| 7 | Jacksonville State | 4 | 14 | 4 | 14 | 0 | 0 | 110 | 27.5 |
| 7 | FIU | 4 | 14 | 8 | 14 | 0 | 0 | 122 | 30.5 |
| 10 | Sam Houston State | 3 | 16 | 6 | 16 | 0 | 0 | 130 | 43.3 |
| 11 | Middle Tennessee State | 4 | 17 | 4 | 17 | 0 | 0 | 131 | 32.8 |
| 11 | Missouri State | 4 | 17 | 4 | 17 | 0 | 0 | 131 | 32.8 |