2022 Atlantic Coast Conference Leaders Rushing Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 1 | 29 | 50 | 1.72 | 0 | 29.00 | 50.00 |
| 1 | Virginia | 1 | 32 | 89 | 2.78 | 0 | 32.00 | 89.00 |
| 3 | Florida State | 1 | 35 | 132 | 3.77 | 1 | 35.00 | 132.00 |
| 3 | Georgia Tech | 1 | 56 | 284 | 5.07 | 1 | 56.00 | 284.00 |
| 5 | Miami (Florida) | 2 | 59 | 123 | 2.08 | 2 | 29.50 | 61.50 |
| 5 | Duke | 2 | 65 | 193 | 2.97 | 2 | 32.50 | 96.50 |
| 5 | Virginia Tech | 2 | 62 | 199 | 3.21 | 2 | 31.00 | 99.50 |
| 5 | North Carolina State | 2 | 59 | 237 | 4.02 | 2 | 29.50 | 118.50 |
| 5 | Wake Forest | 2 | 93 | 400 | 4.30 | 2 | 46.50 | 200.00 |
| 10 | Louisville | 4 | 147 | 452 | 3.07 | 3 | 36.75 | 113.00 |
| 10 | Clemson | 2 | 67 | 269 | 4.01 | 3 | 33.50 | 134.50 |
| 12 | Syracuse | 2 | 83 | 343 | 4.13 | 4 | 41.50 | 171.50 |
| 12 | Boston College | 2 | 77 | 388 | 5.04 | 4 | 38.50 | 194.00 |
| 14 | North Carolina | 3 | 148 | 810 | 5.47 | 6 | 49.33 | 270.00 |