2022 Atlantic Coast Conference Leaders Rushing Defense - Games Lost Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida State | 3 | 141 | 520 | 3.69 | 3 | 47.00 | 173.33 |
| 2 | North Carolina State | 5 | 171 | 591 | 3.46 | 4 | 34.20 | 118.20 |
| 2 | Pittsburgh | 4 | 139 | 531 | 3.82 | 4 | 34.75 | 132.75 |
| 2 | Duke | 4 | 144 | 660 | 4.58 | 4 | 36.00 | 165.00 |
| 5 | Clemson | 3 | 116 | 442 | 3.81 | 5 | 38.67 | 147.33 |
| 6 | Wake Forest | 5 | 192 | 766 | 3.99 | 6 | 38.40 | 153.20 |
| 7 | Louisville | 5 | 200 | 947 | 4.74 | 7 | 40.00 | 189.40 |
| 8 | Virginia | 7 | 303 | 1217 | 4.02 | 11 | 43.29 | 173.86 |
| 8 | Syracuse | 6 | 289 | 1219 | 4.22 | 11 | 48.17 | 203.17 |
| 10 | North Carolina | 5 | 178 | 809 | 4.54 | 12 | 35.60 | 161.80 |
| 11 | Virginia Tech | 8 | 302 | 1330 | 4.40 | 13 | 37.75 | 166.25 |
| 12 | Georgia Tech | 7 | 324 | 1602 | 4.94 | 16 | 46.29 | 228.86 |
| 13 | Miami (Florida) | 7 | 284 | 1262 | 4.44 | 17 | 40.57 | 180.29 |
| 14 | Boston College | 9 | 346 | 1573 | 4.55 | 21 | 38.44 | 174.78 |