2021 National Leaders Long All Purpose Plays - Games at Home Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Brian Battie | S Florida | SO | RB | 6 | 4 | 4 | 3 | 3 | 3 | 3 | 3 |
| 2 | Marcus Jones | Houston | SR | CB | 5 | 5 | 5 | 3 | 3 | 3 | 2 | 2 |
| 3 | Israel Abanikanda | Pittsburgh | SO | RB | 7 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Kris Abrams-Draine | Missouri | SO | DB | 7 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Devon Achane | Texas A&M | SO | RB | 7 | 10 | 4 | 3 | 3 | 1 | 1 | 1 |
| 3 | Carlinos Acie | Navy | SR | SB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Tyrell Ajian | Kentucky | SR | DB | 7 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Calvin Austin III | Memphis | SR | WR | 7 | 4 | 4 | 3 | 3 | 1 | 1 | 1 |
| 3 | Reed Blankenship | MTSU | SR | S | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Zion Bowens | Hawai'i | SR | WR | 6 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Stephan Bracey | Wisconsin | SO | WR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | LD Brown | Okla St | SR | RB | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Treylon Burks | Arkansas | JR | WR | 7 | 6 | 4 | 2 | 1 | 1 | 1 | 1 |
| 3 | Jordan Byrd | SDSU | SR | RB | 8 | 6 | 4 | 2 | 1 | 1 | 1 | 1 |
| 3 | Grayson Cash | UAB | JR | S | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Trey Cobb | App St | SR | ILB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Haaziq Daniels | Air Force | JR | QB | 5 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Derius Davis | TCU | SR | WR | 7 | 5 | 5 | 2 | 2 | 1 | 1 | 1 |
| 3 | Trestan Ebner | Baylor | SR | RB | 7 | 8 | 5 | 3 | 2 | 1 | 1 | 1 |
| 3 | Jahmyr Gibbs | Ga Tech | FR | RB | 6 | 7 | 4 | 3 | 3 | 2 | 1 | 1 |
| 3 | Lideatrick Griffin | Miss St | SO | WR | 6 | 6 | 2 | 2 | 2 | 2 | 1 | 1 |
| 3 | Justin Hall | Ball State | SR | WR | 5 | 6 | 3 | 1 | 1 | 1 | 1 | 1 |
| 3 | Tyler Harrell | Louisville | SO | WR | 7 | 5 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Maquel Haywood | Navy | FR | SB | 3 | 3 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Ahmari Huggins-Bruce | Louisville | FR | WR | 6 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Evan Hull | N'western | SO | RB | 6 | 6 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Jarquez Hunter | Auburn | FR | RB | 7 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | LaMareon James | ODU | FR | CB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Charlie Jones | Iowa | SR | WR | 7 | 7 | 3 | 2 | 2 | 2 | 1 | 1 |
| 3 | Velus Jones Jr. | Tennessee | SR | WR | 8 | 10 | 5 | 2 | 1 | 1 | 1 | 1 |
| 3 | Zonovan Knight | NC State | SO | RB | 7 | 4 | 3 | 1 | 1 | 1 | 1 | 1 |
| 3 | Malik Knowles | Kansas St | JR | WR | 7 | 7 | 5 | 3 | 2 | 1 | 1 | 1 |
| 3 | Marion Lukes | CMU | FR | RB | 6 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Brennan Presley | Okla St | SO | WR | 7 | 7 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Clint Ratkovich | N Illinois | SR | RB | 6 | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| 3 | Nikko Remigio | California | SR | WR | 6 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | T.D. Roof | App St | SR | ILB | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Trayvon Rudolph | N Illinois | FR | WR | 6 | 5 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Ainias Smith | Texas A&M | JR | WR | 7 | 3 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Jaylen Stinson | Duke | SO | S | 7 | 4 | 2 | 2 | 2 | 2 | 2 | 1 |
| 3 | Jacquez Stuart | Toledo | FR | RB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Ja'Sir Taylor | Wk Forest | SR | DB | 6 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Sean Tyler | W Mich | SO | RB | 6 | 5 | 2 | 2 | 2 | 1 | 1 | 1 |
| 3 | Jalen Virgil | App St | SR | WR | 5 | 3 | 3 | 1 | 1 | 1 | 1 | 1 |
| 3 | Anthony Watkins | Tulsa | SO | RB | 6 | 7 | 5 | 3 | 3 | 3 | 1 | 1 |
| 3 | Ja'Cquez Williams | La-Monroe | SR | LB | 6 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Jameson Williams | Alabama | JR | WR | 7 | 11 | 8 | 7 | 5 | 4 | 3 | 1 |
| 3 | Kyren Williams | Notre Dame | SO | RB | 7 | 6 | 4 | 2 | 1 | 1 | 1 | 1 |
| 3 | JT Woods | Baylor | SR | S | 7 | 2 | 2 | 1 | 1 | 1 | 1 | 1 |
| 3 | Winston Wright Jr. | WVU | JR | WR | 6 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |