2021 American Athletic Conference Leaders Passing Defense - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 6 | 134 | 89 | 66.4 | 1123 | 8.4 | 5 | 2 | 146.14 | 22.3 | 187.2 |
| 2 | Cincinnati | 7 | 218 | 113 | 51.8 | 1344 | 6.2 | 8 | 12 | 104.73 | 31.1 | 192.0 |
| 3 | Houston | 9 | 273 | 150 | 54.9 | 1770 | 6.5 | 12 | 11 | 115.87 | 30.3 | 196.7 |
| 4 | Temple | 6 | 171 | 108 | 63.2 | 1205 | 7.0 | 12 | 3 | 142.00 | 28.5 | 200.8 |
| 5 | Tulsa | 7 | 206 | 114 | 55.3 | 1439 | 7.0 | 7 | 6 | 119.39 | 29.4 | 205.6 |
| 6 | UCF | 6 | 197 | 111 | 56.3 | 1236 | 6.3 | 7 | 2 | 118.74 | 32.8 | 206.0 |
| 7 | East Carolina | 6 | 163 | 105 | 64.4 | 1325 | 8.1 | 10 | 5 | 146.82 | 27.2 | 220.8 |
| 8 | South Florida | 6 | 179 | 121 | 67.6 | 1481 | 8.3 | 14 | 3 | 159.56 | 29.8 | 246.8 |
| 9 | Memphis | 5 | 191 | 122 | 63.9 | 1430 | 7.5 | 13 | 3 | 146.08 | 38.2 | 286.0 |
| 10 | SMU | 6 | 196 | 127 | 64.8 | 1830 | 9.3 | 20 | 2 | 174.86 | 32.7 | 305.0 |
| 11 | Tulane | 6 | 219 | 153 | 69.9 | 1954 | 8.9 | 15 | 2 | 165.57 | 36.5 | 325.7 |