2021 American Athletic Conference Leaders Passing Defense - Games in November Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | East Carolina | 4 | 94 | 50 | 53.2 | 640 | 6.8 | 7 | 3 | 128.59 | 23.5 | 160.0 |
| 2 | Cincinnati | 4 | 122 | 69 | 56.6 | 699 | 5.7 | 4 | 3 | 110.59 | 30.5 | 174.8 |
| 3 | Houston | 4 | 152 | 76 | 50.0 | 780 | 5.1 | 4 | 7 | 92.59 | 38.0 | 195.0 |
| 4 | Temple | 4 | 104 | 63 | 60.6 | 802 | 7.7 | 9 | 2 | 150.07 | 26.0 | 200.5 |
| 5 | Tulsa | 4 | 138 | 76 | 55.1 | 912 | 6.6 | 5 | 4 | 116.75 | 34.5 | 228.0 |
| 6 | Tulane | 4 | 134 | 85 | 63.4 | 927 | 6.9 | 6 | 4 | 130.35 | 33.5 | 231.8 |
| 7 | UCF | 4 | 158 | 92 | 58.2 | 933 | 5.9 | 3 | 4 | 109.04 | 39.5 | 233.3 |
| 8 | Memphis | 4 | 141 | 83 | 58.9 | 990 | 7.0 | 4 | 7 | 117.28 | 35.3 | 247.5 |
| 9 | Navy | 3 | 84 | 66 | 78.6 | 783 | 9.3 | 4 | 0 | 172.58 | 28.0 | 261.0 |
| 10 | South Florida | 4 | 117 | 86 | 73.5 | 1112 | 9.5 | 9 | 2 | 175.29 | 29.3 | 278.0 |
| 11 | SMU | 4 | 154 | 94 | 61.0 | 1180 | 7.7 | 10 | 3 | 142.93 | 38.5 | 295.0 |