2021 American Athletic Conference Leaders Passing Defense - Games Won Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 4 | 88 | 51 | 58.0 | 549 | 6.2 | 3 | 2 | 117.07 | 22.0 | 137.3 |
| 2 | Cincinnati | 13 | 385 | 206 | 53.5 | 2188 | 5.7 | 10 | 18 | 100.47 | 29.6 | 168.3 |
| 3 | Temple | 3 | 83 | 47 | 56.6 | 532 | 6.4 | 5 | 2 | 125.53 | 27.7 | 177.3 |
| 4 | Tulane | 2 | 65 | 37 | 56.9 | 358 | 5.5 | 3 | 3 | 109.19 | 32.5 | 179.0 |
| 5 | Houston | 12 | 372 | 200 | 53.8 | 2295 | 6.2 | 14 | 14 | 110.47 | 31.0 | 191.3 |
| 6 | UCF | 9 | 343 | 191 | 55.7 | 1833 | 5.3 | 6 | 9 | 101.10 | 38.1 | 203.7 |
| 7 | South Florida | 2 | 70 | 37 | 52.9 | 431 | 6.2 | 2 | 2 | 108.30 | 35.0 | 215.5 |
| 8 | East Carolina | 7 | 235 | 133 | 56.6 | 1634 | 7.0 | 10 | 10 | 120.54 | 33.6 | 233.4 |
| 9 | SMU | 8 | 249 | 138 | 55.4 | 1954 | 7.8 | 14 | 7 | 134.26 | 31.1 | 244.3 |
| 10 | Tulsa | 7 | 263 | 148 | 56.3 | 1753 | 6.7 | 7 | 7 | 115.72 | 37.6 | 250.4 |
| 11 | Memphis | 6 | 235 | 149 | 63.4 | 1652 | 7.0 | 13 | 4 | 137.31 | 39.2 | 275.3 |