2021 Big 12 Conference Leaders Opponent Penalties - Games in November Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 34 | 231 | 8.5 | 57.8 |
| 2 | Baylor | 4 | 27 | 252 | 6.8 | 63.0 |
| 3 | Kansas | 4 | 26 | 249 | 6.5 | 62.3 |
| 4 | Iowa State | 4 | 20 | 180 | 5.0 | 45.0 |
| 5 | Oklahoma | 3 | 19 | 165 | 6.3 | 55.0 |
| 6 | Texas Tech | 3 | 17 | 152 | 5.7 | 50.7 |
| 7 | West Virginia | 4 | 16 | 140 | 4.0 | 35.0 |
| 8 | Texas | 4 | 14 | 108 | 3.5 | 27.0 |
| 9 | Kansas State | 4 | 11 | 87 | 2.8 | 21.8 |
| 10 | TCU | 4 | 10 | 100 | 2.5 | 25.0 |