2021 Big 12 Conference Leaders Opponent Penalties - Games at Home Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 7 | 55 | 415 | 7.9 | 59.3 |
| 2 | Oklahoma | 7 | 46 | 392 | 6.6 | 56.0 |
| 3 | Texas Tech | 6 | 44 | 380 | 7.3 | 63.3 |
| 4 | TCU | 7 | 38 | 352 | 5.4 | 50.3 |
| 5 | Kansas | 6 | 37 | 270 | 6.2 | 45.0 |
| 6 | Kansas State | 7 | 35 | 287 | 5.0 | 41.0 |
| 7 | Baylor | 7 | 33 | 295 | 4.7 | 42.1 |
| 8 | Iowa State | 6 | 30 | 253 | 5.0 | 42.2 |
| 8 | Texas | 6 | 30 | 233 | 5.0 | 38.8 |
| 10 | West Virginia | 6 | 27 | 221 | 4.5 | 36.8 |