2021 Big 12 Conference Leaders Opponent Penalties - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma | 10 | 64 | 520 | 6.4 | 52.0 |
| 2 | Oklahoma State | 10 | 59 | 501 | 5.9 | 50.1 |
| 3 | Texas Tech | 9 | 55 | 437 | 6.1 | 48.6 |
| 4 | Kansas | 9 | 50 | 434 | 5.6 | 48.2 |
| 5 | Kansas State | 10 | 48 | 377 | 4.8 | 37.7 |
| 6 | TCU | 9 | 42 | 378 | 4.7 | 42.0 |
| 6 | Baylor | 9 | 42 | 367 | 4.7 | 40.8 |
| 8 | West Virginia | 10 | 40 | 321 | 4.0 | 32.1 |
| 9 | Iowa State | 8 | 38 | 298 | 4.8 | 37.3 |
| 10 | Texas | 7 | 34 | 287 | 4.9 | 41.0 |