2021 Big 12 Conference Leaders Opponent Penalties - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 10 | 71 | 544 | 7.1 | 54.4 |
| 2 | Oklahoma | 9 | 59 | 487 | 6.6 | 54.1 |
| 3 | Baylor | 10 | 56 | 495 | 5.6 | 49.5 |
| 4 | Texas Tech | 9 | 54 | 464 | 6.0 | 51.6 |
| 5 | Kansas | 9 | 48 | 414 | 5.3 | 46.0 |
| 6 | Iowa State | 9 | 47 | 437 | 5.2 | 48.6 |
| 7 | Kansas State | 9 | 44 | 370 | 4.9 | 41.1 |
| 8 | West Virginia | 9 | 40 | 334 | 4.4 | 37.1 |
| 9 | Texas | 9 | 38 | 337 | 4.2 | 37.4 |
| 10 | TCU | 9 | 35 | 328 | 3.9 | 36.4 |