2021 Conference USA Leaders Sacks - Games on the Road/Neutral Site Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Western Kentucky | 8 | 25.0 | 141 | 3.13 |
| 2 | Marshall | 7 | 22.0 | 130 | 3.14 |
| 3 | North Texas | 7 | 17.0 | 116 | 2.43 |
| 4 | Old Dominion | 7 | 16.0 | 103 | 2.29 |
| 5 | UTEP | 7 | 15.0 | 114 | 2.14 |
| 6 | UAB | 8 | 14.0 | 105 | 1.75 |
| 7 | Middle Tennessee | 8 | 13.0 | 88 | 1.63 |
| 8 | Louisiana Tech | 6 | 12.0 | 91 | 2.00 |
| 8 | Rice | 6 | 12.0 | 87 | 2.00 |
| 10 | UTSA | 7 | 11.0 | 79 | 1.57 |
| 10 | Southern Mississippi | 6 | 11.0 | 73 | 1.83 |
| 12 | Charlotte | 6 | 9.0 | 74 | 1.50 |
| 13 | Florida Atlantic | 6 | 6.0 | 39 | 1.00 |
| 14 | Florida International | 6 | 3.0 | 20 | 0.50 |