2022 American Athletic Conference Leaders Sacks - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Navy | 11 | 28.0 | 155 | 2.55 |
| 2 | Temple | 9 | 27.0 | 146 | 3.00 |
| 3 | Cincinnati | 9 | 26.0 | 158 | 2.89 |
| 4 | East Carolina | 11 | 25.0 | 170 | 2.27 |
| 5 | Houston | 11 | 24.0 | 130 | 2.18 |
| 6 | Tulane | 11 | 22.0 | 136 | 2.00 |
| 7 | Memphis | 11 | 19.0 | 113 | 1.73 |
| 8 | SMU | 10 | 17.0 | 118 | 1.70 |
| 9 | UCF | 10 | 13.0 | 103 | 1.30 |
| 10 | Tulsa | 10 | 12.0 | 87 | 1.20 |
| 11 | South Florida | 9 | 9.0 | 41 | 1.00 |