2018 American Athletic Conference Leaders Passing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | South Florida | 2 | 49 | 29 | 59.2 | 351 | 7.2 | 1 | 2 | 117.93 | 24.5 | 175.5 |
| 2 | Tulsa | 2 | 46 | 32 | 69.6 | 368 | 8.0 | 3 | 1 | 153.94 | 23.0 | 184.0 |
| 3 | Cincinnati | 2 | 68 | 43 | 63.2 | 381 | 5.6 | 2 | 2 | 114.14 | 34.0 | 190.5 |
| 4 | SMU | 2 | 47 | 30 | 63.8 | 391 | 8.3 | 4 | 2 | 153.29 | 23.5 | 195.5 |
| 5 | Temple | 3 | 99 | 56 | 56.6 | 651 | 6.6 | 8 | 5 | 128.38 | 33.0 | 217.0 |
| 6 | UCF | 2 | 60 | 37 | 61.7 | 557 | 9.3 | 5 | 2 | 160.48 | 30.0 | 278.5 |
| 7 | Connecticut | 1 | 32 | 22 | 68.8 | 295 | 9.2 | 2 | 0 | 166.82 | 32.0 | 295.0 |
| 8 | East Carolina | 2 | 89 | 58 | 65.2 | 655 | 7.4 | 3 | 1 | 135.86 | 44.5 | 327.5 |
| 9 | Memphis | 2 | 72 | 46 | 63.9 | 701 | 9.7 | 5 | 1 | 165.81 | 36.0 | 350.5 |
| 10 | Tulane | 2 | 89 | 62 | 69.7 | 797 | 9.0 | 7 | 2 | 166.34 | 44.5 | 398.5 |
| 11 | Houston | 2 | 109 | 71 | 65.1 | 986 | 9.0 | 5 | 2 | 152.60 | 54.5 | 493.0 |