2018 American Athletic Conference Leaders Passing Defense - Games in August/September Only through 01/07/2019
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 5 | 169 | 83 | 49.1 | 794 | 4.7 | 3 | 4 | 89.70 | 33.8 | 158.8 |
| 2 | UCF | 4 | 113 | 63 | 55.8 | 636 | 5.6 | 3 | 8 | 97.63 | 28.3 | 159.0 |
| 3 | South Florida | 4 | 111 | 57 | 51.4 | 649 | 5.8 | 1 | 5 | 94.42 | 27.8 | 162.3 |
| 4 | Memphis | 5 | 121 | 74 | 61.2 | 843 | 7.0 | 6 | 3 | 131.08 | 24.2 | 168.6 |
| 5 | Tulsa | 4 | 106 | 66 | 62.3 | 702 | 6.6 | 2 | 2 | 120.35 | 26.5 | 175.5 |
| 6 | Temple | 5 | 181 | 101 | 55.8 | 935 | 5.2 | 9 | 7 | 107.87 | 36.2 | 187.0 |
| 7 | East Carolina | 4 | 129 | 75 | 58.1 | 852 | 6.6 | 6 | 1 | 127.42 | 32.3 | 213.0 |
| 8 | SMU | 5 | 153 | 100 | 65.4 | 1118 | 7.3 | 10 | 3 | 144.39 | 30.6 | 223.6 |
| 9 | Navy | 4 | 139 | 92 | 66.2 | 921 | 6.6 | 10 | 4 | 139.83 | 34.8 | 230.3 |
| 10 | Tulane | 5 | 178 | 105 | 59.0 | 1462 | 8.2 | 11 | 6 | 141.63 | 35.6 | 292.4 |
| 11 | Connecticut | 5 | 162 | 119 | 73.5 | 1759 | 10.9 | 17 | 1 | 198.07 | 32.4 | 351.8 |
| 12 | Houston | 4 | 193 | 114 | 59.1 | 1556 | 8.1 | 9 | 3 | 139.07 | 48.3 | 389.0 |