2022 American Athletic Conference Leaders Passing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tulsa | 1 | 24 | 13 | 54.2 | 154 | 6.4 | 2 | 0 | 135.57 | 24.0 | 154.0 |
| 2 | South Florida | 2 | 48 | 29 | 60.4 | 371 | 7.7 | 1 | 2 | 123.88 | 24.0 | 185.5 |
| 3 | Temple | 2 | 47 | 34 | 72.3 | 387 | 8.2 | 2 | 0 | 155.55 | 23.5 | 193.5 |
| 4 | East Carolina | 1 | 33 | 17 | 51.5 | 211 | 6.4 | 1 | 1 | 109.17 | 33.0 | 211.0 |
| 5 | Cincinnati | 3 | 115 | 62 | 53.9 | 635 | 5.5 | 6 | 4 | 110.55 | 38.3 | 211.7 |
| 6 | UCF | 3 | 90 | 54 | 60.0 | 688 | 7.6 | 1 | 0 | 127.88 | 30.0 | 229.3 |
| 7 | Houston | 2 | 82 | 50 | 61.0 | 508 | 6.2 | 5 | 3 | 125.82 | 41.0 | 254.0 |
| 8 | SMU | 2 | 53 | 40 | 75.5 | 510 | 9.6 | 5 | 0 | 187.43 | 26.5 | 255.0 |
| 9 | Tulane | 2 | 83 | 58 | 69.9 | 612 | 7.4 | 6 | 1 | 153.26 | 41.5 | 306.0 |
| 10 | Memphis | 1 | 49 | 38 | 77.6 | 450 | 9.2 | 5 | 1 | 184.29 | 49.0 | 450.0 |