2018 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 9 | 68 | 100 | 13 | 181 | 20.1 |
| 2 | Wake Forest | 8 | 69 | 94 | 13 | 176 | 22.0 |
| 3 | Virginia | 10 | 77 | 82 | 12 | 171 | 17.1 |
| 4 | Clemson | 12 | 80 | 102 | 16 | 198 | 16.5 |
| 5 | Syracuse | 9 | 81 | 86 | 14 | 181 | 20.1 |
| 6 | Florida State | 9 | 82 | 100 | 20 | 202 | 22.4 |
| 6 | Boston College | 9 | 82 | 106 | 14 | 202 | 22.4 |
| 8 | Virginia Tech | 8 | 88 | 60 | 13 | 161 | 20.1 |
| 9 | Miami (Florida) | 10 | 96 | 64 | 16 | 176 | 17.6 |
| 10 | Georgia Tech | 10 | 100 | 92 | 7 | 199 | 19.9 |
| 11 | Pittsburgh | 11 | 102 | 90 | 18 | 210 | 19.1 |
| 11 | North Carolina | 9 | 102 | 83 | 14 | 199 | 22.1 |
| 13 | Duke | 10 | 117 | 101 | 9 | 227 | 22.7 |
| 14 | Louisville | 10 | 133 | 93 | 16 | 242 | 24.2 |