2025 FBS Independents Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 11/19/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Connecticut | 3 | 404 | 842 | 224 | 1246 | 5.56 | 415.3 |
| 2 | Notre Dame | 8 | 687 | 2003 | 539 | 2690 | 4.99 | 336.3 |