2025 Atlantic Coast Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 12/13/2025
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 9 | 13 | 313 | 3 | 1.44 |
| 1 | Duke | 10 | 13 | 167 | 1 | 1.30 |
| 3 | SMU | 10 | 12 | 166 | 1 | 1.20 |
| 3 | Virginia | 11 | 12 | 122 | 2 | 1.09 |
| 5 | Louisville | 9 | 11 | 32 | 0 | 1.22 |
| 6 | Miami (FL) | 9 | 9 | 183 | 2 | 1.00 |
| 6 | Florida State | 10 | 9 | 100 | 0 | 0.90 |
| 8 | NC State | 9 | 7 | 102 | 1 | 0.78 |
| 8 | California | 10 | 7 | 79 | 0 | 0.70 |
| 10 | Boston College | 9 | 5 | 48 | 0 | 0.56 |
| 10 | Clemson | 10 | 5 | 32 | 1 | 0.50 |
| 12 | Syracuse | 9 | 3 | 61 | 0 | 0.33 |
| 12 | Stanford | 9 | 3 | 19 | 1 | 0.33 |
| 12 | Wake Forest | 9 | 3 | 3 | 0 | 0.33 |
| 12 | Georgia Tech | 10 | 3 | 55 | 0 | 0.30 |
| 12 | North Carolina | 10 | 3 | 29 | 0 | 0.30 |
| 12 | Virginia Tech | 10 | 3 | 29 | 0 | 0.30 |