2025 Atlantic Coast Conference Leaders Interceptions - Games at Home Only through 11/22/2025
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | SMU | 6 | 9 | 216 | 3 | 1.50 |
| 1 | Miami (FL) | 8 | 9 | 152 | 2 | 1.13 |
| 3 | Florida State | 7 | 7 | 96 | 0 | 1.00 |
| 4 | Clemson | 7 | 6 | 52 | 0 | 0.86 |
| 5 | Duke | 5 | 5 | 88 | 1 | 1.00 |
| 5 | Virginia | 6 | 5 | 38 | 0 | 0.83 |
| 5 | Boston College | 7 | 5 | 59 | 1 | 0.71 |
| 5 | Louisville | 7 | 5 | 23 | 0 | 0.71 |
| 9 | Pittsburgh | 6 | 4 | 134 | 2 | 0.67 |
| 9 | North Carolina | 6 | 4 | 36 | 0 | 0.67 |
| 9 | NC State | 6 | 4 | 26 | 0 | 0.67 |
| 9 | Virginia Tech | 7 | 4 | 29 | 0 | 0.57 |
| 13 | Syracuse | 5 | 3 | 34 | 0 | 0.60 |
| 13 | Stanford | 5 | 3 | 19 | 1 | 0.60 |
| 15 | California | 5 | 2 | 28 | 0 | 0.40 |
| 15 | Georgia Tech | 6 | 2 | 45 | 0 | 0.33 |
| 15 | Wake Forest | 7 | 2 | 5 | 0 | 0.29 |