2025 Atlantic Coast Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 11/22/2025
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 8 | 12 | 313 | 3 | 1.50 |
| 2 | Virginia | 9 | 9 | 110 | 2 | 1.00 |
| 2 | Miami (FL) | 8 | 8 | 183 | 2 | 1.00 |
| 4 | SMU | 9 | 12 | 166 | 1 | 1.33 |
| 4 | Duke | 8 | 10 | 167 | 1 | 1.25 |
| 4 | NC State | 8 | 7 | 102 | 1 | 0.88 |
| 4 | Stanford | 9 | 3 | 19 | 1 | 0.33 |
| 8 | Louisville | 8 | 9 | 23 | 0 | 1.13 |
| 8 | Florida State | 9 | 8 | 78 | 0 | 0.89 |
| 8 | California | 9 | 6 | 65 | 0 | 0.67 |
| 8 | Boston College | 8 | 5 | 48 | 0 | 0.63 |
| 8 | Syracuse | 8 | 3 | 61 | 0 | 0.38 |
| 8 | Wake Forest | 8 | 3 | 3 | 0 | 0.38 |
| 8 | North Carolina | 9 | 3 | 29 | 0 | 0.33 |
| 8 | Virginia Tech | 9 | 3 | 29 | 0 | 0.33 |
| 8 | Clemson | 9 | 3 | 20 | 0 | 0.33 |
| 8 | Georgia Tech | 9 | 2 | 45 | 0 | 0.22 |