2025 Atlantic Coast Conference Leaders Passes Defended - Games in October Only through 12/20/2025
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | SMU | 4 | 6 | 24 | 30 | 7.50 |
| 2 | Virginia | 3 | 5 | 16 | 21 | 7.00 |
| 3 | Louisville | 3 | 6 | 13 | 19 | 6.33 |
| 4 | Miami (FL) | 3 | 4 | 14 | 18 | 6.00 |
| 5 | Wake Forest | 3 | 3 | 13 | 16 | 5.33 |
| 5 | NC State | 3 | 2 | 14 | 16 | 5.33 |
| 7 | Clemson | 3 | 2 | 13 | 15 | 5.00 |
| 8 | Stanford | 3 | 0 | 14 | 14 | 4.67 |
| 9 | Pittsburgh | 4 | 4 | 13 | 17 | 4.25 |
| 10 | California | 3 | 1 | 11 | 12 | 4.00 |
| 10 | Duke | 2 | 4 | 4 | 8 | 4.00 |
| 12 | Boston College | 4 | 3 | 12 | 15 | 3.75 |
| 12 | North Carolina | 4 | 1 | 14 | 15 | 3.75 |
| 14 | Georgia Tech | 3 | 1 | 9 | 10 | 3.33 |
| 14 | Virginia Tech | 3 | 1 | 9 | 10 | 3.33 |
| 16 | Florida State | 3 | 3 | 5 | 8 | 2.67 |
| 17 | Syracuse | 4 | 2 | 6 | 8 | 2.00 |