2025 Atlantic Coast Conference Leaders Sacks - Games vs. Non-Conference Teams Only through 12/06/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Louisville | 4 | 16.0 | 105 | 4.00 |
| 2 | Pittsburgh | 4 | 12.0 | 88 | 3.00 |
| 3 | Clemson | 4 | 12.0 | 83 | 3.00 |
| 4 | Wake Forest | 4 | 12.0 | 78 | 3.00 |
| 5 | SMU | 4 | 11.0 | 76 | 2.75 |
| 6 | Miami (FL) | 4 | 10.0 | 69 | 2.50 |
| 7 | Virginia Tech | 4 | 8.0 | 62 | 2.00 |
| 8 | Georgia Tech | 4 | 10.0 | 61 | 2.50 |
| 9 | Florida State | 4 | 10.0 | 58 | 2.50 |
| 9 | Boston College | 4 | 8.0 | 58 | 2.00 |
| 11 | Duke | 4 | 10.0 | 56 | 2.50 |
| 12 | California | 4 | 6.0 | 46 | 1.50 |
| 13 | Stanford | 4 | 7.0 | 39 | 1.75 |
| 14 | NC State | 3 | 5.0 | 38 | 1.67 |
| 15 | Syracuse | 4 | 4.0 | 36 | 1.00 |
| 16 | North Carolina | 4 | 4.0 | 28 | 1.00 |
| 17 | Virginia | 3 | 5.0 | 24 | 1.67 |