2022 Atlantic Coast Conference Leaders Sacks - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Louisville | 5 | 17.0 | 126 | 3.40 |
| 2 | Wake Forest | 5 | 16.0 | 116 | 3.20 |
| 3 | North Carolina State | 5 | 11.0 | 102 | 2.20 |
| 4 | Pittsburgh | 5 | 15.0 | 97 | 3.00 |
| 5 | Florida State | 5 | 16.0 | 82 | 3.20 |
| 5 | Duke | 5 | 14.0 | 82 | 2.80 |
| 7 | Virginia Tech | 4 | 10.0 | 66 | 2.50 |
| 8 | Syracuse | 5 | 9.0 | 64 | 1.80 |
| 9 | North Carolina | 5 | 8.0 | 54 | 1.60 |
| 10 | Miami (Florida) | 4 | 10.0 | 53 | 2.50 |
| 11 | Boston College | 4 | 8.0 | 50 | 2.00 |
| 12 | Georgia Tech | 4 | 7.0 | 46 | 1.75 |
| 13 | Virginia | 3 | 8.0 | 45 | 2.67 |
| 14 | Clemson | 5 | 12.0 | 43 | 2.40 |