2025 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 10/24/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 1 | 40 | 177 | 68 | 217 | 3.19 | 217.0 |
| 2 | Florida State | 1 | 43 | 163 | 55 | 206 | 3.75 | 206.0 |
| 3 | Virginia | 1 | 91 | 163 | 67 | 254 | 3.79 | 254.0 |
| 4 | North Carolina | 1 | 21 | 250 | 71 | 271 | 3.82 | 271.0 |
| 5 | Wake Forest | 1 | 158 | 149 | 76 | 307 | 4.04 | 307.0 |
| 6 | Georgia Tech | 1 | 184 | 144 | 81 | 328 | 4.05 | 328.0 |
| 7 | Louisville | 2 | 316 | 268 | 128 | 584 | 4.56 | 292.0 |
| 8 | Clemson | 1 | 78 | 223 | 63 | 301 | 4.78 | 301.0 |
| 9 | SMU | 1 | 53 | 275 | 65 | 328 | 5.05 | 328.0 |
| 10 | Miami (FL) | 2 | 133 | 513 | 126 | 646 | 5.13 | 323.0 |
| 11 | Syracuse | 1 | 142 | 274 | 78 | 416 | 5.33 | 416.0 |
| 12 | California | 1 | 135 | 186 | 53 | 321 | 6.06 | 321.0 |
| 13 | Stanford | 2 | 147 | 683 | 136 | 830 | 6.10 | 415.0 |
| 14 | NC State | 2 | 173 | 725 | 145 | 898 | 6.19 | 449.0 |
| 15 | Duke | 1 | 156 | 270 | 63 | 426 | 6.76 | 426.0 |
| 16 | Boston College | 1 | 93 | 362 | 58 | 455 | 7.84 | 455.0 |
| 17 | Virginia Tech | 1 | 250 | 276 | 62 | 526 | 8.48 | 526.0 |