2025 Atlantic Coast Conference Leaders Scoring Defense - Games vs. FBS Power 5 Conference Teams Only through 10/25/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Wake Forest | 5 | 12 | 10 | 11 | 0 | 0 | 113 | 22.6 |
| 1 | SMU | 6 | 18 | 7 | 17 | 0 | 1 | 148 | 24.7 |
| 1 | Pittsburgh | 6 | 20 | 4 | 18 | 0 | 0 | 150 | 25.0 |
| 1 | Duke | 5 | 17 | 4 | 15 | 0 | 0 | 129 | 25.8 |
| 1 | Virginia | 6 | 20 | 6 | 18 | 0 | 0 | 156 | 26.0 |
| 1 | Stanford | 6 | 21 | 12 | 20 | 0 | 1 | 184 | 30.7 |
| 1 | North Carolina | 5 | 20 | 6 | 20 | 0 | 0 | 158 | 31.6 |
| 1 | Syracuse | 6 | 26 | 8 | 26 | 0 | 0 | 206 | 34.3 |
| 1 | NC State | 5 | 21 | 10 | 20 | 0 | 0 | 176 | 35.2 |
| 10 | Georgia Tech | 6 | 15 | 7 | 11 | 1 | 0 | 124 | 20.7 |
| 10 | Clemson | 6 | 14 | 11 | 11 | 1 | 0 | 130 | 21.7 |
| 10 | Louisville | 4 | 12 | 6 | 10 | 1 | 0 | 102 | 25.5 |
| 10 | Florida State | 5 | 18 | 6 | 17 | 1 | 0 | 145 | 29.0 |
| 10 | Virginia Tech | 6 | 23 | 9 | 21 | 1 | 0 | 188 | 31.3 |
| 10 | Boston College | 6 | 28 | 10 | 27 | 1 | 0 | 227 | 37.8 |
| 16 | Miami (FL) | 4 | 7 | 3 | 5 | 2 | 0 | 60 | 15.0 |
| 16 | California | 6 | 20 | 6 | 16 | 2 | 0 | 158 | 26.3 |