2025 Atlantic Coast Conference Leaders Scoring Defense - Games vs. FBS Power 5 Conference Teams Only through 12/06/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 9 | 15 | 7 | 12 | 2 | 0 | 127 | 14.1 |
| 2 | Clemson | 10 | 25 | 15 | 20 | 2 | 0 | 219 | 21.9 |
| 3 | Virginia | 11 | 30 | 12 | 28 | 0 | 0 | 244 | 22.2 |
| 4 | SMU | 10 | 26 | 14 | 25 | 0 | 1 | 225 | 22.5 |
| 5 | Louisville | 9 | 24 | 12 | 21 | 1 | 1 | 205 | 22.8 |
| 6 | Wake Forest | 9 | 25 | 17 | 24 | 0 | 0 | 225 | 25.0 |
| 7 | Florida State | 10 | 31 | 11 | 28 | 2 | 0 | 251 | 25.1 |
| 8 | Pittsburgh | 9 | 31 | 7 | 29 | 0 | 0 | 236 | 26.2 |
| 9 | Georgia Tech | 10 | 33 | 12 | 28 | 1 | 0 | 264 | 26.4 |
| 10 | Stanford | 9 | 29 | 15 | 28 | 0 | 1 | 249 | 27.7 |
| 11 | California | 10 | 35 | 12 | 31 | 2 | 0 | 281 | 28.1 |
| 12 | Duke | 10 | 36 | 11 | 32 | 2 | 0 | 285 | 28.5 |
| 12 | North Carolina | 10 | 37 | 9 | 34 | 1 | 0 | 285 | 28.5 |
| 14 | Virginia Tech | 10 | 38 | 15 | 36 | 1 | 0 | 311 | 31.1 |
| 15 | NC State | 9 | 33 | 18 | 29 | 1 | 0 | 283 | 31.4 |
| 16 | Syracuse | 9 | 38 | 13 | 38 | 0 | 0 | 305 | 33.9 |
| 17 | Boston College | 9 | 39 | 16 | 36 | 1 | 0 | 320 | 35.6 |