2022 Big 12 Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas | 4 | 617 | 953 | 290 | 1570 | 5.41 | 392.5 |
| 2 | Iowa State | 3 | 453 | 675 | 195 | 1128 | 5.78 | 376.0 |
| 3 | Baylor | 3 | 507 | 742 | 206 | 1249 | 6.06 | 416.3 |
| 4 | TCU | 5 | 831 | 1279 | 337 | 2110 | 6.26 | 422.0 |
| 5 | Oklahoma State | 3 | 627 | 901 | 238 | 1528 | 6.42 | 509.3 |
| 6 | Kansas State | 5 | 1037 | 1225 | 347 | 2262 | 6.52 | 452.4 |
| 7 | Texas Tech | 3 | 728 | 588 | 192 | 1316 | 6.85 | 438.7 |
| 8 | Kansas | 3 | 801 | 633 | 206 | 1434 | 6.96 | 478.0 |
| 9 | West Virginia | 4 | 482 | 1279 | 246 | 1761 | 7.16 | 440.3 |
| 10 | Oklahoma | 4 | 1101 | 1248 | 311 | 2349 | 7.55 | 587.3 |